Corresponding author: Danijela Videnović zelenivenacvet@gmail.com Summary: Changes in haematological and biochemical values can indicate a disease that can be of different origins. Systemic changes can be represented equally due to viral, bacterial or certain immunological changes in cats, which can be observed as a change in reference values in haematology and biochemistry. During the examination, white blood cells, red blood cells, hemoglobin, transaminases, urea, creatinine, and globulins are most often monitored. Lymphopenia (FIV, FIP, FeLV) or neutropenia (FeLV ) can be observed in certain viral diseases. In that period, cats often show visible changes in the clinical picture when the owner comes to the veterinarian to consult about the treatment of the animal. Neutropenia with anaemia, thrombocytopenia are not rare in FeLV, FIV infected cats. These types of changes can occur independetly of each other in the mentioned diseases. Anaemia can be one of the indicators for FIP, but so can thrombocytoopenia. Proper sampling, the way the sample is processed can affect the final result. A high- quality history is important in the further steps of diagnosis. All this is very important to us when we decide on how to treat cats in the case of indetified changes at the level of haematology and biochemistry. The availability of preparations that will affect the strengthening of immunity based on beta glucan, vitamin K for thrombocytopenia, and iron supplements for anaemia are part of supporative therapy. Most often, immunosuppressants are included. Antibiotics are included according to the established diagnosis. Preparations based on silymarin and SAMe products have a positive effect on the reduction of transaminases (ALT,ALP) in case of damage to parenchymatous organs, and improve liver in FIP, FIV-afflicted cats. When and how to start therapy in such animals is influenced only by the clinical condition of the pet, i.e., the presence of vomiting and diarrhoea or the absence of appetite and respiratory changes. In the case of the above-mentioned present symptoms, start compensation with electrolytes, and clear solutions of supplements. Changes in haemotological and biochemical findings help in therapy and more closely determining the diagnosis of certain viral diseases, but to establish a definitive diagnosis, it is necessery to perform other tests using available methods: rapid tests, PCR diagnostics, serological analysers. Key words: FiLV, FIP, FIV, lymphopenia, neutropenia, thrombocytopenia XXVI SYMPOSIUM OF EPIYOOTIOLOGIST AND EPIDEMIOLOGIST BOOK OF ABSTRACTS, 10-12. APRIL 2024. Koviljaca SPA ISBN 978-86-83115-52-5 COBISS.SR-ID 141341705 CIP 636.09:616(048)
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Danijela Videnović Autor za korespodenciju: zelenivenacvet@gmail.com Kratak sadržaj: Promene u hematološkim i biohemijskim vrednostima nam mogu ukazati na oboljenje koje može biti različitog porekla. Sistemske promene mogu biti zastupljene podjednako zbog virusnih, bakterijskih ili pojedinih imunoloških promena kod mačaka što se može uočiti kao promena u referentnim vrednostima u hematologiji i biohemiji. Tokom ispitivanja najčešće se prate ćelije bele krvne loze, crvene krvne loze, hemoglobin, transaminaze, urea, kreatinin, globulini. Kod pojedinih virusnih oboljenja mogu se primetiti limfopenija (FIV, FIP, FeLV ) ili neutropenija (FeLV). U tom periodu mačke su najčešće sa vidljivim promenama u kliničkoj slici kada vlasnik dolazi do veterinara da se posavetuje oko lečenja životinja. Neutropenija sa anemjom, trombocitopenijom nisu retke kod FeLV, FIV obolelih mačaka. Ove vrste promena mogu se javiti nezavisno jedna od druge kod navedenih oboljenja. Anemija može biti jedan od pokazatelja za FIP ali i trombocitopenija. Pravilno uzorkovanje, način obrade uzorka mogu uticati na krajnji rezultat. Kvalitetna anamneza je bitna u daljim koracima dijagnostike. Sve ovo nam je jako važno kada donosimo odluku o načinu terapiranja mačaka u slučaju indetifikovanih promena na nivou hematologije i biohemije. Dostupnost preparata koji će uticati na jačanje imuniteta na bazi beta glukama, vitamin K za trombocitopeniju, gvožđe u suplementima za anemiju su deo potporne terapije. Najčešće se uključuju imunosupresivi. Antibiotici se daju prema postavljenoj dijagnozi. Preparati na bazi silimarina i SAMe proizvodi pozitivno utiču na smanjenje transaminaza (ALT, ALP) u slučaju oštećenja parenhimatoznih organa, poboljšavaju regeneraciju jetre kod FIP, FIV obolelih mačaka. Kada i kako započeti terapiju kod ovakvih životinja utiče kliničko stanje ljubimca odnosno, prisustvo povraćanja i proliva ili odsustvo apetita i respiratorne promene. Kod navedenih prisutnih simptoma započeti nadoknadu sa elektrolitima, bistrim rastvorima suplemenata. Promene u hematološkim i biohemijskim nalazima pomažu u terapiranju i bližem određivanju dijagnoze kod pojedinih virusnih oboljenja ali za postavljenje definitivne dijagnoze neophodno je uradti ostala testiranja dostupnim metodama: brzi testovi, PCR dijagnostika, serološki analajzeri. Ključne reči: FiLV, FIP, FIV, limfopenija,neutropenija, trombocitopenija ISBN 978-86-83115-52-5 COBISS.SR-ID 141341705 CIP 636.09:616 (048) Zbornik kratkih sadržaja, Banja Koviljača, 10-12. april 2024. XXVI SIMPOZIJUM EPIZOOTIOLOGA I EPIDEMIOLOGA ROYAL VET, MEDIPORT, ROYAL VET, MEDIPORT, ROYAL VET SmartLab smartLAB |
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